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Larotrectinib Exceeds 90% Response Rate in TRK+ Pediatric Cancers

Larotrectinib induced an “unprecedented” objective response rate of 93% in patients with TRK fusion–positive solid tumors.

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Nilotinib Granted FDA Approval for Pediatric CML

Based on data from 2 clinical trials, nilotinib (Tasigna) has been approved by the FDA for the first- and 2nd-line treatment of pediatric patients aged 1 year and older with Philadelphia chromosome–positive chronic myeloid leukemia in the chronic phase.

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EMA Recommends Extension of Therapeutic Indications for Fosaprepitant

It is indicated for prevention of nausea and vomiting associated with highly and moderately emetogenic chemotherapy in adult and paediatric patients

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FDA Grants Accelerated Approval to Blinatumomab for the Treatment of B-cell Precursor ALL

It is indicated in adult and paediatric patients in first or second complete remission with minimal residual disease

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Asian AYA Cancer Care Survey

This survey is organised by the ESMO/SIOPE Cancer in Adolescent and Young Adults (AYA) Working Group following successful mapping of the European AYA cancer care landscape.

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Social Network Index Developed to Assess the Support Resources of Adolescent and Young Adult Cancer Survivors

A functional social network index was developed that is specific for adolescent and young adult survivors of cancer

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Larotrectinib FDA Submission Completed for TRK Fusion Cancer

A rolling new drug application has been completed for larotrectinib (LOXO-101) for the treatment of adult and pediatric patients with locally advanced or metastatic solid tumors harboring an NTRK gene fusion.

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FDA Approves Nilotinib for Paediatric patients with Newly Diagnosed or Resistant/Intolerant Ph-Positive CML in Chronic Phase

2018-03-28 22:16:00

Approval is based on results in paediatric patients from CAMN107A2120 and CAMN107A2203 studies