Tag Archive for: tenofovir alafenamide

Gender-related differences in safety

Gender-related differences in safety after switching to BIC/TAF/FTC

Human immunodeficiency virus (HIV), one of most serious public health challenges in the world, has already affected approximately 37.6 million people across the globe in 2020 and new infections in 2020 are estimated to be 1.5 million. Bictegravir/ Emtricitabine/ tenofovir (BIC/TAF/FTC) is a fixed-dose combination tablet consisting of an integrase inhibitor and two nucleoside reverse transcriptase inhibitors for the treatment of HIV infection. This HIV medication was approved by the United States Food and Drug Administration (USFDA) in 2018 due to the excellent efficacy outcomes in clinical trials. Real-world safety data of BIC/TAF/FTC was presented at the 18th European AIDS Conference in 2021 and summarised below.

Effect of HIV infection on growth and bone density in peripubertal children under antiretroviral therapy

Effect of HIV infection on growth and bone density in peripubertal children under antiretroviral therapy

As reported in The Lancet Child and Adolescent Health 2021, a cross-sectional study from the IMVASK cohort enrolled and investigated human immunodeficiency virus (HIV)-infected children who were previously treated with antiretroviral therapy (ART) for at least 2 years, and were compared against children of the same age without HIV.

comparison-of-the-metabolic-changes-from-the-tango-trial-a-post-hoc-analysis

Comparison of the metabolic changes from the TANGO trial: a post-hoc analysis

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